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Written By Rohan Wiese
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Updated on May 22nd, 2025
Summary: Microsoft Outlook is an indispensable tool for managing emails, calendars, contacts, and more. However, users may encounter the ‘Outlook PST file is in use and cannot be accessed’ error, which disrupts workflow. This error generally prevents Outlook from accessing the PST file. Therefore, it hinders normal Outlook operations. In this guide, we’ll explore the causes of this error and provide effective solutions to resolve it. If the problem is due to PST file corruption, using Outlook PST Recovery Software is the best way. Download Now Purchase Now
You might have seen such an error message occasionally:
“The file C:\Users\username\AppData\Local\Microsoft\Outlook\username.pst is in use and cannot be accessed. Close any application that is using this file, and then try again. You might need to restart your computer.
A PST file is a backup data file of Outlook and is essential. It encompasses all data such as emails, attachments, metadata, contacts, calendar, etc. But this Outlook error has drastic after effects like data loss, system slowdown, application crash, failure to launch, etc. Even sometimes, Outlook is inaccessible.
Here are probable reasons that can lead to this error in Outlook:
So, figure out the real cause of the error in your Outlook application and move ahead to get the perfect troubleshooting solution.
This section describes the stepwise procedure to troubleshoot the error. Firstly, try the manual steps; if it did not work, run the professional software.
First of all, you need to ensure that no Outlook processes are running in the background. Do as follows:
If the local cache is causing the issue, try disabling Cached Exchange Mode. Here is how to do it:
If any faulty add-in is causing the error ‘Outlook PST file is in use and cannot be accessed’, run Outlook in Safe Mode. This will help to disable add-ins that might be causing conflicts. Follow the steps:
Microsoft provides a built-in tool to repair corrupt PST files. ScanPST.exe (or Outlook Inbox Repair Tool) helps in cases where you encounter such an Outlook error and the PST cannot be accessed. Here are the steps to run it:
This is a free tool by Outlook to repair PST files, but for severe PST corruption, it may fail. Therefore, you can purchase premium software to fix the Outlook PST is in use and cannot be accessed error.
Using a professional PST repair tool works better if you have a PST file corruption. Aryson Outlook PST Recovery Software is the most demanded utility among Outlook users to fix all PST errors. This tool has a simple interface, thus facilitating quick data recovery. Moreover, it can handle all levels of PST corruption with three recovery modes.
With this excellent software, you can also save PST data as a backup in MBOX, DBX, EML, MSG, New PST, or Save for Archive. Even users can restore only selective data after recovery, to prevent the oversized PST issue.
To know more about the software, try the free demo tool that only restricts restoring data for free.
Also Read: How to Fix Microsoft Outlook Inbox Repair Tool Not Responding?
The Outlook error- “Outlook PST File is in Use and Cannot Be Accessed” can entirely disrupt your workflow. However, it is curable with the right methodology. With the various manual and professional solutions outlined above, you can resolve the issue and prevent future occurrences. Moreover, if you ensure regular maintenance and are cautious of faulty add-ins, you can keep Outlook running smoothly. However, we have suggested a professional software for cases where you face PST file corruption.
Ans- This error typically occurs when another process, backup tool, antivirus program, or another instance of Outlook is accessing the PST file. It can also result from improper shutdowns or corrupted PST files. You need to take proper preventive measures to handle this.
Ans- Yes, a corrupted PST file can hinder Outlook’s ability to access emails, contacts, and other data. This leads to errors like “PST file is in use and cannot be accessed.” Repairing the PST file with the Aryson PST Recovery Tool can restore normal functionality.
Ans- There are multiple ways to resolve this issue, depending on the cause:
✅ End any Outlook-related processes in the background
✅ Run Outlook in Safe Mode to disable add-ins.
✅ Use the Inbox Repair Tool (Scanpst.exe) to repair the PST file.
✅ Or, recover Outlook data using ARyson PST Repair Tool.
Ans- Yes, ending the Outlook.exe process from Task Manager is safe. It can help resolve the Outlook PST cannot be accessed issues. Sometimes Outlook appears closed but is still running in the background. This action can free up the PST file for access.
About The Author:
Rohan Wiese is a Technical Writer at Aryson Technologies. He is an expert Email Forensic, Cloud Computing, and a passionate nerd with over 10 years of experience in technical content writing. He writes about Cloud Migration, Database Recovery, Email Backup, Windows, Mac, and Tech.
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